Middle Tennessee just pulled off the biggest upset in NCAA Tournament history over Michigan State, and everyone's brackets are busted

Middle Tennessee State University just pulled off the biggest upset of the 2016 NCAA Tournament, and perhaps of all time.

In a 2-15 matchup with Michigan State, Middle Tennessee shocked the world, winning 90-81.

In doing so, the team became just the eighth No. 15 seed to beat a No. 2 seed in tournament history, overcoming a -16.5 spread that favored MSU.

The massive upset likely ruined a lot of brackets. According to ESPN, MSU, who many thought should be a No. 1 seed, was selected to win in the round of 32 by 91% of ESPN bracket users, win in the Sweet 16 game by 80.9% of users, win in the Final Four by 38.6% of users and win the entire tournament by 22% of users.

Middle Tennessee took the sports world by surprise right out of the gate, surging to a 15-2 lead, from which they never looked back. They were led by an even performance from their starters, getting 21 points from forward Reggie Upshaw, with double-digit scoring from their other four starters.

For MTSU, it's a pretty historic moment:

Yet they handled their business casually.

They're onto the next round, where they'll meet Syracuse.